Intraoperative Pth Assay

 Human IgG SPARCL™ Assay

IGG-SP-20 1 kit
EUR 500

Human IgG antibody Laboratories manufactures the intraoperative pth assay reagents distributed by Genprice. The Intraoperative Pth Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact pth assay. Other Intraoperative products are available in stock. Specificity: Intraoperative Category: Pth Group: Assay

True Blue

5.0mg
EUR 595
  • Smiles Code: N=C(N)C1=CC=C2C(C=C(/C=C/C3=CC4=C(C=CC(C(N)=N)=C4)O3)O2)=C1.Cl.Cl

True Blue

10mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

1g Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

1mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

50mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

5mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

5(mg
EUR 635

Assay information

MURF3 Intrachain TR-FRET Assay Kit

78555 384 reactions
EUR 1905
Description: The MURF3 intrachain TR-FRET Assay Kit utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on MURF3, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetic analyses of polyubiquitination.

CellMetrix Intracellular GSH Assay Kit**

MBS258014-100Tests 100Tests
EUR 380

CellMetrix Intracellular GSH Assay Kit**

MBS258014-5x100Tests 5x100Tests
EUR 1735

PTH/PTHrP-R Antibody

G220-100ul 100μl
EUR 217
Description: PTH/PTHrP-R Rabbit Polyclonal Antibody

PTH/PTHrP-R Antibody

G220-50ul 50μl
EUR 143.5
Description: PTH/PTHrP-R Rabbit Polyclonal Antibody

SMURF1 intrachain TR-FRET Assay Kit

78303 384 rxns.
EUR 1520
Description: Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1),  a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and efficiency of ubiquitination are largely determined by the E3 enzyme, which directs the last step of the Ub-conjugating cascade by binding to both an E2~Ub conjugate and a substrate protein. This step ensures the transfer of Ub from E2~Ub to the substrate, leading to its mono- or poly-ubiquitination.The SMAD ubiquitination regulatory factor 1 (SMURF1) is a HECT-type E3 Ub ligase that regulates TGF-β/BMP pathways via ubiquitination of key signal transducers (SMAD1, SMAD2, or SMAD5), or TGF-β receptor I. SMURFs play a critical role in cell-type specification, tissue and organ development by regulating planar cell polarity signaling and convergent extension. SMURFs can also accelerate tumor progression, invasion, and metastasis as they regulate ubiquitination and subsequent proteasomal degradation of tumor-suppressing proteins including p53 as well as various cell signaling proteins. That is why SMURF1 and especially its Ub ligase activity is an attractive potential drug target in cancer immunotherapy. Like most E3 ligases, SMURF1 ubiquitinates itself.The SMURF1 intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit, designed to measure SMURF1 auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on SMURF1, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses of polyubiquitination.

SMURF2 intrachain TR-FRET Assay Kit

78304 384 rxns.
EUR 1520
Description: Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1),  a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and efficiency of ubiquitination are largely determined by the E3 enzyme, which directs the last step of the Ub-conjugating cascade by binding to both an E2~Ub conjugate and a substrate protein. This step ensures the transfer of Ub from E2~Ub to the substrate, leading to its mono- or poly-ubiquitination.The SMAD ubiquitination regulatory factor 2 (SMURF2) is a HECT-type E3 Ub ligase that regulates TGF-β/BMP pathways via ubiquitination of key signal transducers (SMAD1, SMAD2, or SMAD5), or TGF-β receptor I. SMURFs play a critical role in cell-type specification, tissue and organ development by regulating planar cell polarity signaling and convergent extension. SMURFs can also accelerate tumor progression, invasion, and metastasis as they regulate ubiquitination and subsequent proteasomal degradation of tumor-suppressing proteins including p53 as well as various cell signaling proteins. That is why SMURF2 and especially its Ub ligase activity is an attractive potential drug target in cancer immunotherapy. Like most E3 ligases, SMURF2 ubiquitinates itself.The SMURF2 intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit, designed to measure SMURF1 auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on SMURF2, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses of polyubiquitination.

DCAF15 Intrachain TR-FRET Assay Kit

78543 384 rxns.
EUR 1550
Description: The DCAF15 Intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit designed to measure DCAF15 auto-ubiquitination activity in a homogeneous 384-reaction format. It utilizes Europium-labeled Ubiquitin (donor) and Cy5-labeled Ubiquitin (acceptor) to complete the TR-FRET pairing. This assay measures poly-ubiquitination since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on DCAF15. As a homogenous assay, it requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses.

Cereblon intrachain TR-FRET Assay Kit

78301 384 rxns.
EUR 1750
Description: Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1),  a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and efficiency of ubiquitination are largely determined by the E3 enzyme, which directs the last step of the Ub-conjugating cascade by binding to both an E2~Ub conjugate and a substrate protein. This step ensures the transfer of Ub from E2~Ub to the substrate, leading to its mono- or poly-ubiquitination.The Cereblon (CRBN) protein via its interaction with the DNA damage-binding protein-1 (DDB1), Cullin 4 (Cul4A or Cul4B), and regulator of Cullins 1 (RoC1) forms the functional E3 Ub ligase complex. In this complex, Cereblon functions as a substrate receptor that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Cereblon complex is involved in many biological processes including cell proliferation and apoptosis. That is why it has been employed for targeted protein degradation in the treatment of cancer. Like most E3 ligases, Cereblon complex ubiquitinates itself and this auto-ubiquitination promotes its Ub ligase activity.The Cereblon intrachain TR-FRET Assay Kit is a sensitive high-throughput screening (HTS) TR-FRET Assay Kit, designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes a Europium cryptate-labeled Ub (donor) as well as Cy5-labeled Ub (acceptor) to complete the TR-FRET pairing. Since both the TR-FRET donor and acceptor are incorporated into poly-ubiquitin chains formed on Cereblon, this FRET-based assay requires no time-consuming washing steps, making it especially suitable for HTS applications as well as real-time kinetics analyses of polyubiquitination.

Lysosomal Intracellular Activity Assay Kit

K448-50 each
EUR 652.8

Intracellular Total ROS Activity Assay Kit

9144 100
EUR 341

Intracellular Total ROS Activity Assay Kit

MBS258376-100Tests 100Tests
EUR 490

Intracellular Total ROS Activity Assay Kit

MBS258376-5x100Tests 5x100Tests
EUR 2235

Parathyroid Hormone (PTH) Magnetic Luminex Assay Kit

LKU606970-96T 96T
EUR 869.4

Parathyroid Hormone (PTH) Magnetic Luminex Assay Kit

LKU606973-96T 96T
EUR 944.2

Parathyroid Hormone (PTH) Magnetic Luminex Assay Kit

LKU606978-96T 96T
EUR 894.7

Parathyroid Hormone (PTH) Magnetic Luminex Assay Kit

LKU606980-96T 96T
EUR 993.6