Ligand Binding Assay

IgG Assay

KAI-014 1 Kit Ask for price

Human IgG antibody Laboratories manufactures the ligand binding assay reagents distributed by Genprice. The Ligand Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact ligand assay. Other Ligand products are available in stock. Specificity: Ligand Category: Binding Group: Assay

True Blue

5.0mg
EUR 595
  • Smiles Code: N=C(N)C1=CC=C2C(C=C(/C=C/C3=CC4=C(C=CC(C(N)=N)=C4)O3)O2)=C1.Cl.Cl

True Blue

5(mg
EUR 635

True Blue

5x5(mg
EUR 2705

True Blue

10mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

1g Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

1mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

True Blue

50mg Ask for price
  • SMILES: N=C(C1=CC=C(OC(/C=C/C2=CC3=CC(C(N)=N)=CC=C3O2)=C4)C4=C1)N.Cl.Cl
  • Formula: C20H18Cl2N4O2
Description: True Blue

Assay information

THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1A2 50 ug
EUR 660
  • Nuclear receptors
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B1 50 ug
EUR 498
  • Nuclear receptors
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B3 50 ug
EUR 498
  • Nuclear receptors
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PPARG-LBD. Purified GST-tagged human Peroxisome proliferator-activated receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1C3 50 ug
EUR 720
  • Nuclear receptors
Description: Drug discovery, Nuclear receptors, purified recombinant protein

VHL Binding Assay Kit

78805 96 Reactions Ask for price
  • Applications: Titrate or screen small molecule inhibitors of VHL binding to the probe in drug discovery and high throughput (HTS) applications.
Description: The Von Hippel–Lindau tumor suppressor (VHL) Binding Assay Kit is a homogeneous assay which measures the binding of VHL to the high-affinity VHL fluorescent probe (BDY FL VH032) using Fluorescence Polarization (FP) . In addition, the kit includes the VHL inhibitor VH298 for use as an inhibitor control. This assay takes advantage of the fluorescent substrate BDY FL VH032. Using this kit, only one step on a 96-well plate is required. The BDY FL VH032 is incubated with the VHL complex in the presence of a compound of interest to produce a change in fluorescent polarization. The FP signal is measured using a fluorescent microplate readercapable of measuring fluorescence polarization.Need us to run inhibitor screens or profile your compounds against VHL Binding? Check out ourUbiquitination Screening Services.

Annexin V Binding Assay

TBS2108 100 tests
EUR 200

Cereblon Binding Assay Kit

79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

EGF Receptor Antibody (ligand binding site)

GWB-601D00 0.1 mg Ask for price

EZH2-EED Binding Assay Kit

52066 384 rxns.
EUR 1665
Description: The EZH2-EED Binding Assay Kit is designed to measure the inhibition of the_x000D_protein-protein interaction between EZH2 and EED. The key to this kit is the specific binding of EZH2 to EED. With this kit, only two_x000D_simple steps on a microtiter plate are required. First, incubate a sample containing EZH2, EED_x000D_and an inhibitor of choice. Next, incubate with a mixture of acceptor and donor beads, followed_x000D_by reading the Alpha-counts.

PCSK9-LDLR Binding Assay Kit

GWB-PS6C8F 96 reactions Ask for price

PCSK9 (His) -LDLR Binding Assay Kit

78813-1 96 Reactions Ask for price
  • Applications: Screen small molecules and antibodies that inhibit the binding of PCSK9 to LDLR ectodomain.
Description: The PCSK9 (His) -LDLR Binding Assay Kit is an ELISA-type 96-well format assay designed for screening and profiling purposes. Moreover, two pre-formulated assay buffers are supplied to validate PCSK9-LDLR binding affinity in either neutral or acidic binding conditions. The assay takes advantage of the high sensitivity of detection of His-tag PCSK9 by Anti-His HRP-antibody. First, the LDLR ectodomain is coated on a 96-well plate. Next, PCSK9 is incubated with LDLR on the plate. Finally, the plate is treated with Anti-His HRP-antibody followed by addition of an HRP substrate to produce chemiluminescence, measured using a chemiluminescence reader.Figure 1: Illustration of the ELISA-based PCSK9 (His) -LDLR Binding Assay Kit.Need us to run inhibitor screens or profile your compounds against PCSK9 (His) -LDLR? Check out ourPCSK9 Screening Services.

PCSK9 (His) -LDLR Binding Assay Kit

78813-2 384 Reactions Ask for price
  • Applications: Screen small molecules and antibodies that inhibit the binding of PCSK9 to LDLR ectodomain.
Description: The PCSK9 (His) -LDLR Binding Assay Kit is an ELISA-type 96-well format assay designed for screening and profiling purposes. Moreover, two pre-formulated assay buffers are supplied to validate PCSK9-LDLR binding affinity in either neutral or acidic binding conditions. The assay takes advantage of the high sensitivity of detection of His-tag PCSK9 by Anti-His HRP-antibody. First, the LDLR ectodomain is coated on a 96-well plate. Next, PCSK9 is incubated with LDLR on the plate. Finally, the plate is treated with Anti-His HRP-antibody followed by addition of an HRP substrate to produce chemiluminescence, measured using a chemiluminescence reader.Figure 1: Illustration of the ELISA-based PCSK9 (His) -LDLR Binding Assay Kit.Need us to run inhibitor screens or profile your compounds against PCSK9 (His) -LDLR? Check out ourPCSK9 Screening Services.

Retinol Binding Protein Assay Kit

abx098452-Hitachi7060R130ml2R220ml1 Hitachi 7060; R1 30ml×2 R2 20ml×1
EUR 604.8
  • Shipped within 5-12 working days.

Retinol Binding Protein Assay Kit

abx098452-Hitachi7170R130ml2R220ml1 Hitachi 7170; R1 30ml×2 R2 20ml×1
EUR 604.8
  • Shipped within 5-12 working days.

Retinol Binding Protein Assay Kit

abx098452-Hitachi7170R160ml1R220ml1 Hitachi 7170; R1 60ml×1 R2 20ml×1
EUR 604.8
  • Shipped within 5-12 working days.

Retinol binding protein Assay Kit

SH0246 R1:45ml×1R2:15ml×1
EUR 1000

TLR3, Ligand Binding Domain (Toll-like Receptor 3, CD283)

MBS643157-01mg 0.1mg
EUR 590